FoxO3a drives a regulatory network associated with therapeutic response in metastatic prostate cancer
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ABSTRACT: Anaysis of the response to different therapeutic agents at the transcriptional level. The design of the experiment allows to determine how the combination target therapy (Rapamycin + PD0325901) treatment shifts the transcriptome towards a less aggressive or even a wild type phenotype more efficiently than conventional chemotherapy (Docetaxel). It also allows exploring the molecular chages involved in the transition from a non metastatic to a metastatic prostate cancer mouse model.
ORGANISM(S): Mus musculus
PROVIDER: GSE32053 | GEO | 2022/10/04
REPOSITORIES: GEO
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