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SP1 as a Potential Therapeutic Target in Hypoxia-Associated Osteoporosis: Evidence from Multi-Omics [RNA-seq]

ABSTRACT: Primary rat BMSCs were cultured under 1% O₂, and osteogenic/adipogenic differentiation was assessed by ALP activity, staining, immunofluorescence, and qRT-PCR. ATAC-seq and RNA-seq were integrated to characterize hypoxia-induced chromatin and transcriptional changes.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE320546 | GEO | 2026/03/04

REPOSITORIES: GEO

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