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ECM1 produced by hepatic stellate cells serves as gate keeper of liver homeostasis in hepatic fibrosis

ABSTRACT: Hepatic stellate cell (HSC) activation is central to liver fibrosis, but emerging evidence suggests HSC homeostatic activity. We compared HSC functions in parenchymal injury (CCl₄-driven) versus metabolic dysfunction-associated steatohepatitis (MASH; choline deficient high fat diet, CD-HFD) and identify therapeutic targets preserving HSC homeostatic functions.

ORGANISM(S): Mus musculus

PROVIDER: GSE322720 | GEO | 2026/08/26

REPOSITORIES: GEO

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