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Estrogenic modulation of inflammation-related genes in male rats following volume overload


ABSTRACT: The purpose of this study was to determine whether estrogen had an effect on inflammation-related genes that contribute to this estrogen-mediated cardioprotection. Volume overload on the heart was induced by aortocaval fistula in 8 week old male Sprague Dawley rats and genes of interest in shams, fistula , and fistula +estrogen were identified using an inflammatory PCR array.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE32296 | GEO | 2011/09/23

SECONDARY ACCESSION(S): PRJNA146369

REPOSITORIES: GEO