Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression profile characteristics and clinical significance of plasma extracellular RNA(exRNA) in patients with rheumatoid arthritis

ABSTRACT: Plasma from rheumatoid arthritis(RA) patients and healthy controls underwent Heber sequencing to profile exRNA in RA and assess their association with disease activity.

ORGANISM(S): Homo sapiens

PROVIDER: GSE324400 | GEO | 2026/04/14

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Expression profile characteristics and clinical significance of plasma extracellular RNA(exRNA) in patients with rheumatoid arthritis

Project description:Expression profile characteristics and clinical significance of plasma extracellular RNA(exRNA) in patients with rheumatoid arthritis

| PRJNA1435029 | ENA

Rheumatoid arthritis

Project description:Rheumatoid arthritis (RA) is a chronic, inflammatory joint disease of unknown etiology and pronounced inter-patient heterogeneity. To characterize RA at the molecular level and to uncover key pathomechanisms, we performed whole-genome gene expression analyses. Synovial tissues from rheumatoid arthritis patients were compared to those from osteoarthritis patients and to normal donors. Keywords: disease state analysis

2004-11-04 | GSE1919 | GEO

Altered plasma tRNA-derived small RNA profiles and their clinical relevance in rheumatoid arthritis

Project description:Plasma from rheumatoid arthritis(RA) patients and healthy controls underwent high-throughput small-RNA sequencing to profile tRNA-derived small RNAs(tsRNAs) in RA and assess their association with disease activity.

2026-04-14 | GSE320093 | GEO

Synovial fluid proteome in rheumatoid arthritis

Project description:Rheumatoid arthritis (RA) is a chronic autoinflammatory disorder that affects small joints. Despite intense efforts, there isno definitive marker yet for early diagnosis RA and for monitoring the progression of this disease. We sought to catalog the proteins present in the synovial fluid of patients with rheumatoid arthritis. To identify lower abundance proteins, we undertook two approaches – we depleted the abundant proteins using a multiple affinity removal system (MARS14) column and we enriched glycoproteins using a lectin affinity column. The peptides were analyzed by LC-MS/MS on a high resolution Fourier transform mass spectrometer.

2016-06-13 | PXD000740 | Pride

Protein profiling of plasma extracellular vesicles from rheumatoid arthritis patients.

Project description:Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovial inflammation and cartilage/bone damage. Cytokines like IL-1 and TNF, play a crucial role in the pathophysiology of RA but have limited diagnostic and prognostic value. Recently, extracellular vesicles (EVs) have gained attention in the pathogenesis of this disease, but which processes they reflect in RA is unknown. Therefore, we identified and quantified proteins in plasma-derived EVs from RA patients (RA-pEVs) by mass spectrophotometry (MS) and compared these proteins to pEVs from healthy controls (HC). The observed RA-pEV proteins were coupled to clinical or laboratory parameters to investigate which RA disease process is reflecting by circulating EVs.

2023-12-13 | PXD046058 | Pride

Single cell RNA-seq for PBMC from rheumatoid arthritis patient

Project description:The transcriptome of PBMC from rheumatoid arthritis patient hasn't been compenhensively profiled, and heterogeneous characteristics of blood monocytes in RA patients are much unknown. We performed the single cell transcriptomic analysis of PBMC from rheumatoid arthritis (RA) patient, and monocyte populations were extracted during the analysis. CD127 expression associated expression pattern of inflammatory genes was identified in RA patient's blood monocytes.

2020-11-10 | GSE159117 | GEO

Single-cell immunoprofiling of synovial helper T cell of rheumatoid arthritis patients.

Project description:Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by chronic destructive arthritis. Although helper T cells are involved in the pathogenesis of RA, the characteristics of synovium-infiltrating CD4+ T cells are still largely unknown. In this study, we investigated synovium-infiltrating helper T cells of rheumatoid arthritis patients

2023-05-18 | GSE216245 | GEO

Expression data from Rheumatoid Arthritis synovial tissue samples

Project description:Rheumatoid arthritis (RA) is a complex and clinically heterogeneous autoimmune disease. Microarray analysis of 83 synovial samples provides insight into the expression-level differences between patients at the site of disease activity. Synovial samples from Rheumatoid Arthritis patients were obtained during joint resection and profiled using microarrays.

2014-04-22 | E-GEOD-48780 | biostudies-arrayexpress

Potential biomarker discovery in rheumatoid arthritis serum samples using LC–MS/MS

Project description:To discover potential biomarkers in rheumatoid arthritis (RA) serum samples, we performed LC–MS/MS analysis to identify RA-associated proteins.

2026-05-23 | PXD078759 | Pride

Comparison of miRNA from healthy donors versus Rheumatoid arthritis patients

Project description:miRNA differential expression in Rheumatoid arthritis(RA) blood: Microarray analysis of miRNAs in blood from RA and healthy donors.

2016-09-06 | GSE18097 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data