Effect of TAPIR on mNSCs in self-renewing conditions

ABSTRACT: Cellular translation rates are hypothesized to impact various cellular processes. Changes in rRNA expression levels are often implicated in diseases. This study reports a novel approach using a CRISPR activation (referred to as TAPIR) to manipulate rRNA levels. Induction of rRNA stimulates protein synthesis and cell proliferation, amongst others

ORGANISM(S): Mus musculus

PROVIDER: GSE324584 | GEO | 2026/07/01

REPOSITORIES: GEO