Comparative DNA methylation profiling of highly invasive and parental patient-derived glioblastoma stem-like cells using the Illumina Infinium MethylationEPIC array
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ABSTRACT: This dataset contains genome-wide DNA methylation profiles of patient-derived glioblastoma stem-like cells (GSCs) generated using the Illumina Infinium MethylationEPIC BeadChip array. A highly invasive subpopulation was established by serial transwell invasion selection and compared with the parental, non-selected population. The dataset was generated to identify DNA methylation changes associated with a stable invasive phenotype in glioblastoma cells and to enable analysis of regulatory regions and transcription factor motif-associated methylation patterns linked to invasion.
ORGANISM(S): Homo sapiens
PROVIDER: GSE324664 | GEO | 2026/08/31
REPOSITORIES: GEO
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