Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

RNA-seq analysis of FDX2-inducible knockout (FDX2-iKO) ES2 ovarian carcinoma cells under normoxic and hypoxic conditions

ABSTRACT: This dataset provides RNA-seq profiles of human ES2 ovarian carcinoma cells harboring a doxycycline-regulated, inducible knockout of the FDX2 gene (FDX2-iKO ES2 cells). In this Tet-off system, FDX2 expression is maintained in the presence of doxycycline, while FDX2 knockout is induced upon doxycycline withdrawal. Cells were cultured under normoxic (20% O₂) or hypoxic (3% O₂) conditions, with or without doxycycline. The aim of this study was to define the transcriptional consequences of FDX2 loss under varying oxygen levels. Raw read counts and processed data are provided to facilitate comparative expression analyses.

ORGANISM(S): Homo sapiens

PROVIDER: GSE324929 | GEO | 2026/07/01

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

RNA-seq analysis of FDX2-inducible knockout (FDX2-iKO) ES2 ovarian carcinoma cells under normoxic and hypoxic conditions

Project description:RNA-seq analysis of FDX2-inducible knockout (FDX2-iKO) ES2 ovarian carcinoma cells under normoxic and hypoxic conditions

| PRJNA1438110 | ENA

Lung Cancer Exosomes Hypoxic v Normoxic

Project description:Exosomes derived from NSCLC cells under normoxic or hypoxic conditions were compared to identify hypoxic associated enrichment of proteins in exosomes.

2023-03-10 | PXD038587 | Pride

Differential expressions of microRNAs under normoxic and hypoxic conditions

2014-04-18 | GSE56870 | GEO

Gene expression profile of MM1S under normoxic and hypoxic conditions

Project description:MM1S cells have been cultured under normoxic and hypoxic conditions, and gene expression profiling has been performed using the Affymetrix Human Genome U133 Plus 2.0 array.

2014-08-01 | GSE52315 | GEO

Human NK cells under normoxic and hypoxic conditions

Project description:Human NK cells under normoxic and hypoxic conditions

| PRJNA479833 | ENA

Differential expressions of microRNAs under normoxic and hypoxic conditions

Project description:Outcome prediction classifiers were successfully constructed through expression profiling of a total of 1,329 miRNAs in MKN1, gastric cancer cell line under normoxic and hypoxic conditions. In the study presented here, MKN1 under normoxic and hypoxic conditions was used to acquire expression profiles of a total 1,329 unique miRNAs.

2014-04-18 | E-GEOD-56870 | biostudies-arrayexpress

Gene expression profile of MM1S under normoxic and hypoxic conditions

Project description:MM1S cells have been cultured under normoxic and hypoxic conditions, and gene expression profiling has been performed using the Affymetrix Human Genome U133 Plus 2.0 array. We used microarrays to dissect the possible changes occurring at the mRNA level in normoxic cells versus hypoxic cells.

2014-08-01 | E-GEOD-52315 | biostudies-arrayexpress

RNA-seq analysis of normoxic and hypoxic tumor-associated macrophages

Project description:mRNA expression data in FACS sorted CD11b+ F4/80+ tumor-associated macrophages that are derived from normoxic (as characterized by low GLUT1-expression on the cell membrane) or hypoxic (as characterized by high GLUT1-expression on the cell membrane) area's of Lewis Lung Carcinoma tumors injected subcutaneously in either wild type or REDD1 (DDIT4) knockout mice.

2018-01-01 | E-MTAB-5032 | biostudies-arrayexpress

Gene expression following transverse aortic constriction in mice housed under normoxic or hypoxic conditions

Project description:mRNA expression profiles from C57/Bl6J mouse hearts 3 days after transverse aortic constriction (TAC) or sham surgery. Mice were house under normoxic (21% O2) or hypoxic conditions (12% O2).

2024-12-02 | GSE218522 | GEO

11 Neuroblastoma cell lines under normoxic and hypoxic conditions

Project description:Hypoxia is a low oxygen condition that occurs in the developing tumor mass and that is associated with poor prognosis and resistance to chemo- and radio-therapy. The definition of the hypoxia gene signature is fundamental for the understanding of tumor biology, as in the case of neuroblastoma, the most common pediatric solid tumor. The issue of identifying a significant group of variables in microarray gene expression experiments is particularly difficult due to the typical high dimensional nature of the data and great effort has been spent in the development of feature selection techniques. Our main goal is to define a robust hypoxia gene signature in neuroblastoma cell lines. A set of 11 neuroblastoma cell lines were cultured under normoxic and hypoxic conditions for 18 hours, and their gene expression profiles were measured with Affymetrix GeneChip HG-U133 Plus 2.0. We used the l1-l2 regularization framework in order to select the significant probesets defining hypoxic versus normoxic cell lines.

2009-09-30 | GSE17714 | GEO

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

Tweets

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data