High-resolution spatial transcriptomics of human adrenal neoplasms

ABSTRACT: To characterize the tumor microenvironment and elucidate mechanisms of immune evasion in malignant adrenal tumors, we performed spatial transcriptomics (Visium HD) on pathological specimens from adrenocortical adenoma (ACA) and pheochromocytoma mixed tumor. Using each cell’s spatial coordinates and gene expression profiles, we inferred tumor cell–immune cell interactions.

ORGANISM(S): Homo sapiens

PROVIDER: GSE325991 | GEO | 2026/03/30

REPOSITORIES: GEO