Transcriptomics

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Transcriptomic profiling of primary mouse aortic smooth muscle cells treated with inflammatory macrophage-conditioned medium


ABSTRACT: Inflammatory cell infiltration is a hallmark of many vascular diseases, but the specific molecular mechanisms by which macrophage-derived signals influence smooth muscle cell (SMC) phenotype remain poorly defined. This study utilized bulk RNA sequencing to elucidate the transcriptomic shifts driven by the inflammatory macrophage secretome.

ORGANISM(S): Mus musculus

PROVIDER: GSE326694 | GEO | 2026/06/03

REPOSITORIES: GEO

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