Astragaloside IV Modulates Oxidative Stress and Osteoimmune–Wnt Signaling in Ovariectomized Rats: An Integrated Study of RNA Sequencing, Molecular Docking, and Experimental Validation

ABSTRACT: Postmenopausal osteoporosis (PMOP) is characterized by high-turnover bone loss and oxidative stress. Astragaloside IV (AS-IV) exhibits antioxidant and immunomodulatory activities, yet its skeletal effects and mechanistic basis in ovariectomized (OVX) models remain incompletely defined.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE326719 | GEO | 2026/04/01

REPOSITORIES: GEO