Reciprocal Zeb1-Fgfr3 Regulation Controls Skeletal Development

ABSTRACT: Mesenchymal stem cell (MSC) lineage commitment during bone development is orchestrated by specific transcriptional factors, but the molecular drivers remain elusive. Here, we identify the zinc-finger transcription factor ZEB1 as a pivotal regulator of early skeletogenesis in perichondrial stem cells.

ORGANISM(S): Mus musculus

PROVIDER: GSE327414 | GEO | 2026/04/15

REPOSITORIES: GEO