Limonin ameliorates metabolic dysfunction-associated steatohepatitis in mice

ABSTRACT: Limonin (Lim), a triterpenoid predominantly enriched in citrus fruits, exhibits diverse pharmacological activities, yet its therapeutic efficacy and mechanistic basis in metabolic dysfunction-associated steatohepatitis (MASH) remain poorly defined. Here, we show that Lim attenuates liver fibrosis and hepatocellular apoptosis in MASH mouse models induced by a methionine–choline-deficient (MCD) diet.

ORGANISM(S): Mus musculus

PROVIDER: GSE328199 | GEO | 2026/04/30

REPOSITORIES: GEO