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Elucidating the mechanism underlying sepsis- induced hemolysis, RNA_seq of red pulp macrophages

ABSTRACT: An RNA-seq of red pulp macrophages 2 hours after CLP or sham to investigate differenial gene expression and functional effects.

ORGANISM(S): Mus musculus

PROVIDER: GSE328303 | GEO | 2026/08/01

REPOSITORIES: GEO

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Elucidating the mechanism underlying sepsis- induced hemolysis, RNA_seq of Kupffer cells

Project description:An RNA-seq of kupffer cells 2 hours after CLP or sham to investigate differenial gene expression and functional effects.

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Elucidating the mechanism underlying sepsis- induced hemolysis, RNA_seq of red pulp macrophages

Project description:Elucidating the mechanism underlying sepsis- induced hemolysis, RNA_seq of red pulp macrophages

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Elucidating the mechanism underlying sepsis- induced hemolysis, RNA_seq of Kupffer cells

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Tissue printing: splenic red pulp macrophages of once-malaria infected mice are transcriptionally identical to prenatally seeded red pulp macrophages from uninfected mice.

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Project description:Pitaya is a new fruit crop, whose exotically colored fruits have excellent nutritional and antioxidant properties. In this study, the primary metabolite profiles of three pitaya cultivars i.e. 'Guanhuahong' (red peel with red pulp), 'Guanhuabai' (red peel with white pulp) and 'Guanhuahongfen' (red peel with pink pulp) were investigated using GC-MS and Ultraviolet–visible spectroscopy. In the fruit pulp, levels of starch, organic acids, and inositol decreased as the fruit matured. Glucose, fructose, sucrose and sorbitol contents increased gradually during fruit maturation and reached their highest levels in the pulp at the mature stage. Citramalic acid was identified for the first time in the pulp of Hylocereus species. Higher levels of total phenols, flavonoids and antioxidant activities were detected in the peel than in the pulp during fruit maturation of all three cultivars. The finding of higher levels of total phenols and flavonoids in the pitaya peel than in the pulp at the mature stage suggests that pitaya peels are a good source of natural phenols and flavonoids.

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