Single-cell resolution spatial transcriptomics of a mucinous tubular and spindle cell carcinoma using CosMX

ABSTRACT: This dataset investigates the spatial organization of a human mucinous tubular and spindle cell carcinoma using single-cell resolution spatial transcriptomics. The dataset comprises 22 fields of view from a primary tumor specimen profiled using the CosMX Human 1K panel. Gene program activity scores were estimated using gene programs previously identified from single-cell RNA sequencing data. Local malignant cell density, defined as the fraction of neighboring cells classified as malignant, was quantified and analyzed in relation to gene program activity to assess spatial associations within the tumor microenvironment.

ORGANISM(S): Homo sapiens

PROVIDER: GSE328460 | GEO | 2026/07/20

REPOSITORIES: GEO