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Single-cell transcriptomic analysis of CD8+ T cells from peripheral blood of WT and Dusp2-/- mice

ABSTRACT: Virtual memory CD8+ T (TVM) cells are a distinct subset of antigen-inexperienced cells with rapid effector potential, but their regulatory checkpoints remain elusive. Here, using single-cell transcriptomic profiling, we found that depletion of DUSP2 drives the expansion of CD44super-high TVM subset with heightened effector signatures.

ORGANISM(S): Mus musculus

PROVIDER: GSE329034 | GEO | 2026/04/29

REPOSITORIES: GEO

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