Deciphering Senescence-Associated Mechanisms Through Cell Painting & Transcriptomics

ABSTRACT: Senescence is a key pathomechanism across chronic diseases but highly heterogeneous. In this study we demonstrate that high-content imaging and transcriptomics can jointly shed light on senescence in vitro, distinguishing healthy and chemically induced senescence, differentiation from quiescence and characterization of senolytic response.

ORGANISM(S): Homo sapiens

PROVIDER: GSE329184 | GEO | 2026/09/23

REPOSITORIES: GEO