Transcriptomics

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Effects of GLI1, GLI3, and GLI1/3 knockdown on rhematoid arthritis synovial fibroblasts stimulated with TNF-alpha


ABSTRACT: To investigate effects of GLI1, GLI3, and GLI1/3 knockdown on rhematoid arthritis synovial fibroblasts (RASFs) stimulated with TNF-alpha, we pre-treated RASFs (n = 3) with siControl (siCtrl) or siGLI1, siGLI3, or GLI1/3 for 72 hours, and then treated them with TNF-alpha (10 ng/mL) for 24 hours and conducted RNA-seq analysis.

ORGANISM(S): Homo sapiens

PROVIDER: GSE329806 | GEO | 2026/06/10

REPOSITORIES: GEO

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