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Genetic interaction analysis of PIH1 deletion strains (GIM screen)

ABSTRACT: A S. cerevisiae strain with deletion of the PIH1 gene was combined with two collections of yeast mutants: one in which non-essential genes were deleted and one in which an long 3' UTR extension has been added to the mRNA of essential genes (GIM method, Decourty et al., 2008). Combined double-mutant deletion cells growth was quantified using barcodes that are specific for each gene mutation. A reference population was obtained by mixing the results of 15 GIM screens DNA prior to barcode amplification and labeling (Decourty et al., NAR 2021).

ORGANISM(S): Saccharomyces cerevisiae S288C Saccharomyces cerevisiae

PROVIDER: GSE329834 | GEO | 2026/05/10

REPOSITORIES: GEO

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