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Bulk RNA-seq of dorsal root ganglion (DRG) neuron with 3 conditions

ABSTRACT: Bulk RNA sequencing was performed to compare mRNA expression profiles across six experimental conditions: monoculture of primary dorsal root ganglion (DRG) neurons isolated from C57BL/6J mice; conditioned medium from EO771 cells applied to DRG neurons; and direct co-culture of EO771 and DRG neurons followed by fluorescence-activated cell sorting (FACS) to DRG neuron population. The aim was to identify transcriptional programs regulated by tumor–neuron interactions, including acute gene expression changes, intercellular signaling pathways, and broader pathway-level alterations. The dataset is intended for differential expression analysis, pathway enrichment, and hypothesis generation for downstream functional studies.

ORGANISM(S): Mus musculus

PROVIDER: GSE330238 | GEO | 2026/05/15

REPOSITORIES: GEO

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