Transcriptomics

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Fibroblast-derived CCL2 function in skin infection


ABSTRACT: This dataset includes bulk RNA-seq, single-cell RNA-seq, and spatial transcriptomic analyses performed to investigate the role of fibroblast-derived CCL2 in cutaneous host defense against Staphylococcus aureus infection. Samples include control and infected mouse skin, as well as fibroblast-specific Ccl2-deficient skin, and were used to define transcriptional, cellular, and spatial changes associated with impaired CCL2 signaling during skin infection.

ORGANISM(S): Mus musculus

PROVIDER: GSE330279 | GEO | 2026/05/11

REPOSITORIES: GEO

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