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Effect of chronic ethanol consumption on rat pancreas

ABSTRACT: Male Wistar rats weighing 90-120 g were acclimatized for one week and fed standard laboratory chow, at which time the animals were divided into two groups. Animals were then pair-fed for 8 weeks a regular laboratory chow and water “ad libitum” or Lieber-DeCarli diet (36% calories from ethanol). Control animals received the iso-caloric amount of dextrose to replace ethanol. After 8 weeks of differential feeding rats were euthanized, the pancreas immediately dissected and stored at -80?C until RNA isolation. RNA expression was analyzed using Affymetrix RAE230A gene chips Keywords: stress response, disease state analysis

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE3311 | GEO | 2006/07/01

SECONDARY ACCESSION(S): PRJNA93341

REPOSITORIES: GEO

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