RNA transcript changes in Itpr3 p.R2523C Effector Memory CD4+ T cells

ABSTRACT: Mutations in inositol trisphosphate receptor type 3 (ITPR3) have been linked to immunodeficiency, including an expansion of effector memory (EM) CD4+ T cells within peripheral tissues. We developed a mouse model that genocopied a single allelic (p.R2524C) ITPR3 mutation found in humans.

ORGANISM(S): Mus musculus

PROVIDER: GSE332595 | GEO | 2026/05/21

REPOSITORIES: GEO