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SnRNA-seq, snATAC-seq and Stereo-seq datasets of mouse striatum at different time points in MCAO/R

ABSTRACT: Ischemic stroke constitutes a multifaceted neurological affliction involving diverse cell types in the brain. A lack of dynamic transcriptional and chromatin accessibility data in the post-stroke period remains a key barrier to elucidating the underlying mechanisms. We employed snRNA-seq, snATAC-seq and Stereo-seq to construct a comprehensive transcriptional and chromatin accessibility landscape of the striatum covering the acute (0 h), subacute (24 h), and chronic (7 d, 14 d) phases post-MCAO/R mice.

ORGANISM(S): Mus musculus

PROVIDER: GSE332910 | GEO | 2026/09/09

REPOSITORIES: GEO

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