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Transcriptomic response of largemouth bass (Micropterus nigricans) gill and spleen to bacterial coinfection

ABSTRACT: Largemouth bass (Micropterus salmoides) were challenged with Aeromonas veronii (Av), Aeromonas hydrophila (Ah), Flavobacterium columnare (Fc), and coinfections (AvFc, AhFc), alongside mock-challenged and pre-challenge controls. Gill and spleen tissues were sampled at 0h (pre-challenge baseline), 12h, and 24h post-challenge. RNA-Seq was performed on 161 samples (79 gill, 82 spleen; 6 biological replicates per treatment/timepoint group, 10 for pre-challenge). Three gill samples were excluded due to low mapping rates consistent with gDNA contamination (11B3G, 15J2G, 29R3G). Differential expression analysis was performed using DESeq2 across 72 pairwise contrasts per tissue.

ORGANISM(S): Micropterus salmoides

PROVIDER: GSE333434 | GEO | 2026/07/31

REPOSITORIES: GEO

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