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Alcohol Withdrawal Is Associated with Altered PCBP1 RNA Binding in the Hippocampus

ABSTRACT: Withdrawal from chronic alcohol exposure disrupts brain gene expression and RNA splicing programs. The multifunctional RNA-binding protein PCBP1 has been previously implicated in RNA alternative splicing in the hippocampus during withdrawal from chronic alcohol (ethanol) exposure. However, the transcriptome-wide RNA targets associated with PCBP1 during ethanol withdrawal are not known. Here, we generated a map of PCBP1 RNA binding in the hippocampus of male and female rats following a 24-hour withdrawal from chronic ethanol exposure using RNA immunoprecipitation and sequencing (RIP-Seq) with an antibody to PCBP1

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE333698 | GEO | 2026/08/24

REPOSITORIES: GEO

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Alcohol Withdrawal Is Associated with Altered PCBP1 RNA Binding in the Hippocampus

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