Lactylation-Dependent DDX18 Nucleolar Escape Regulates CD44 mRNA Stability to Drive Fibrotic Progression in Kidney Disease [RIP-Seq]

ABSTRACT: To investigate the function of K116 lactylation of DDX18, we performed RIP-seq analysis in DDX18-deficient HK-2 cells transfected with either DDX18-WT or the DDX18-K116R mutant plasmid to compare the RNA-binding profiles of DDX18-WT and DDX18-K116R.

ORGANISM(S): Homo sapiens

PROVIDER: GSE333824 | GEO | 2026/07/17

REPOSITORIES: GEO