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The Transcriptomic landscape of Kaposi Sarcoma Herpes Virus

ABSTRACT: Kaposi sarcoma (KS) is a tumor caused by Kaposi sarcoma herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8). Unlike other virus-associated tumors, where disease progression often continues even after viral eradication, KS requires the persistent presence of KSHV for disease progression. This unique dependency underscores the potential of strategies targeting the virus to also target the tumor. This study aims to characterize the expression of KSHV viral proteins and identify factors associated with differences in viral gene expression, ultimately formulating treatment targets.

ORGANISM(S): Homo sapiens

PROVIDER: GSE334036 | GEO | 2026/06/09

REPOSITORIES: GEO

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