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PDE5a Inhibition Restricts Cancer Metastasis by Disrupting NPC1-Mediated Cholesterol Trafficking Through a Non-canonical cGMP-Dependent Pathway

ABSTRACT: To evaluate the effects of Sildenafil Citrate on the transcriptome, we performed differential gene expression profiling on three different cancer cell lines: 4T1 (breast carcinoma), MC38 (colon adenocarcinoma), and LLC (Lewis lung carcinoma) post-treatment

ORGANISM(S): Mus musculus

PROVIDER: GSE334363 | GEO | 2026/06/04

REPOSITORIES: GEO

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