PRMT5 activity sustains histone production to maintain genome integrity

ABSTRACT: Using time-resolved nascent transcriptional profiling, quantitative proteomics, and imaging, we show that PRMT5 activity is required to sustain histone transcription and histone protein synthesis during S phase.

ORGANISM(S): Homo sapiens

PROVIDER: GSE334611 | GEO | 2026/09/07

REPOSITORIES: GEO