Trained immunity links hematopoietic stem cell aging to aging-associated inflammation

ABSTRACT: SIRT3 is a mitochondrial NAD+-dependent deacetylase. To investigate the role of SIRT3 in hematopoietic stem cell aging, we generated and characterized mouse models overexpressing SIRT3.

ORGANISM(S): Mus musculus

PROVIDER: GSE335257 | GEO | 2026/06/24

REPOSITORIES: GEO