Transcriptomic profiling of unsorted day-17 iPSC-derived megakaryocytic differentiation cultures carrying SLFN14 p.Q93W

ABSTRACT: This study investigated transcriptomic alterations associated with impaired megakaryocytic maturation in a patient-derived induced pluripotent stem cell (iPSC) model of SLFN14-related thrombocytopenia. Bulk RNA-seq was performed on iPSC-derived megakaryocytic cells from a control iPSC line and an SLFN14 p.Q93W carrier-derived iPSC line.

ORGANISM(S): Homo sapiens

PROVIDER: GSE336171 | GEO | 2026/06/22

REPOSITORIES: GEO