Spatial analysis reveals cellular microenvironments and mechanisms of inflammation and injury in acute interstitial nephritis

ABSTRACT: Single-cell spatial transcriptomics (10x Genomics Xenium) of human kidney biopsy tissue profiling acute interstitial nephritis (AIN), acute tubular injury (ATI), and reference kidney. The dataset maps the cellular microenvironments and signaling driving inflammation and tubular injury, including interferon-driven CXCL9-CXCR3 networks and complement (C3-C3AR1) signaling.

ORGANISM(S): Homo sapiens

PROVIDER: GSE336890 | GEO | 2026/08/18

REPOSITORIES: GEO