Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Transcriptomic profiling of lung tissue from wild-type and TMPRSS2-knockout rats

ABSTRACT: This RNA-seq dataset profiles lung tissues from wild-type Sprague-Dawley rats and crTMPRSS2 (TMPRSS2-knockout) rats. The experiment was used to assess transcriptional changes associated with loss of TMPRSS2, including altered expression of inflammatory, innate immune, and adaptive immune response-related genes.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE337134 | GEO | 2026/07/07

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other
	GSE337134_KOvsWT_deg_all.txt.gz	Txt
	GSE337134_gene_count.txt.gz	Txt
	GSE337134_gene_fpkm.txt.gz	Txt

Items per page:

1 - 4 of 4

Similar Datasets

Sprague-Dawley rats

Project description:Sprague-Dawley rats Raw sequence reads

| PRJNA1116584 | ENA

Sprague Dawley rats

Project description:Sprague Dawley rats Raw sequence reads

| PRJNA548844 | ENA

Rattus norvegicus strain:Sprague-Dawley rats

Project description:Transcriptome of Sprague-Dawley rats

| PRJNA517238 | ENA

Rats, heart tissue, iTRAQ proteomics

Project description:Male Sprague-Dawley rats were randomly divided into (1) mock surgery (MS) group, mock surgery after EP (EPMS) group, myocardial ischemia (MI) group and MI after EP (EPMI) group. Twenty-four hours after MI or mock surgery , left ventricular tissues below the ligation were collected for the iTRAQ proteomics.

2020-04-23 | PXD017765 | Pride

Regional brain expression maps for microRNAs in rats

Project description:MicroRNA transcriptional profiling of male Sprague-Dawley rats rat brains comparing microRNA abundance in five different brain regions.

2009-11-17 | GSE16725 | GEO

Nrf2 activation ameliorates behavioural and brain oscillatory function alterations induced by prenatal valproic acid exposure selectively in female rats

Project description:In this dataset we include the expression data obtained by dissected prefrontal cortical tissue from sprague-dawley rats exposed to saline or valproic acid on gestation day 12.5 in utero. This data was used to obtain prefrontal cortical genes in adolescence to determine sex differences in a model of autism spectrum disorder.

2025-11-29 | GSE311498 | GEO

Transcriptome profiling of mRNAs in cortex of rats with cerebral ischemia and reperfusion

Project description:We analyzed transcriptomic characteristic of motor cortex from Sprague-Dawley rats brain with cerebral ischemia and reperfusion (CIR).

2024-01-12 | GSE222704 | GEO

Profiling livers from LPS-treated rats

Project description:This program addresses the gene signature associated with LPS-treated liver in rat. Specifically, which genes are differentially expressed in livers of the Sprague Dawley rats treated with LPS?

2013-03-22 | GSE38078 | GEO

Integrated Proteomic Profiling of Inner Ear and Systemic Fluids Following Noise-Induced Hearing Loss in Rats

Project description:This project investigates proteomic changes associated with noise-induced hearing loss (NIHL) using a rat model. Sprague–Dawley rats were exposed to acute broadband noise (110 dB SPL for 1 hour), resulting in an approximately 40 dB auditory threshold shift measured by cochlear nerve compound action potential (CAP). Proteomic profiling was performed on perilymph, cochlear-sourced cerebrospinal fluid (CSF), whole blood, and plasma to identify molecular responses to acoustic trauma. Comparative analysis revealed significant protein alterations across local cochlear fluids and systemic samples, highlighting pathways related to metabolism, immune responses, complement/coagulation, and lipid regulation. The dataset provides a resource for exploring molecular mechanisms of NIHL and identifying potential systemic biomarkers associated with cochlear injury.

2026-03-20 | PXD075720 | JPOST Repository

Rattus norvegicus strain:Sprague-Dawley rats

Project description:Rattus norvegicus strain:Sprague-Dawley rats Genome sequencing

| PRJNA686507 | ENA