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Single-cell transcriptomic profiling of pituitary adenoma from patient with Cushing's disease

ABSTRACT: We performed single-cell transcriptomic profiling of a pituitary adenoma from a patient with a rare subtype of Cushing's disease using the 10x Genomics platform. The analysis revealed the cellular landscape of the tumor, identifying distinct cell populations, their transcriptional signatures, and the degree of intratumoral heterogeneity. These findings provide insights into the cellular architecture of this uncommon ACTH-secreting pituitary adenoma variant.

ORGANISM(S): Homo sapiens

PROVIDER: GSE337357 | GEO | 2026/07/07

REPOSITORIES: GEO

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