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MiRNA sequencing of plasma sEVs from diabetic foot rats treated with tibial cortex transverse transport

ABSTRACT: This study aimed to characterize the miRNA expression profile of plasma-derived small extracellular vesicles (sEVs) from diabetic foot rats treated with tibial cortex transverse transport. Plasma sEVs were isolated from peripheral blood samples of diabetic foot rats treated with either tibial transverse transport or sham surgery, followed by small RNA sequencing. Differentially expressed miRNAs were analyzed to explore the potential regulatory mechanisms by which tibial transverse transport promotes diabetic wound repair, with particular focus on angiogenesis, inflammatory regulation, immune modulation, and tissue regeneration.

ORGANISM(S): Rattus norvegicus

PROVIDER: GSE337487 | GEO | 2026/07/04

REPOSITORIES: GEO

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