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Microarray Analysis of Toxicogenomic Effects of Triclosan on Mycobacterium bovis BCG

ABSTRACT: Global gene expression analysis of Mycobacterium bovis BCG following Triclosan treatment using Affymetrix GeneChip arrays. Results from this study provide insight into the molecular mechanisms underlying the cellular response of Mycobacterium bovis BCG to Triclosan

ORGANISM(S): Mycobacterium tuberculosis variant bovis BCG

PROVIDER: GSE33800 | GEO | 2012/12/25

SECONDARY ACCESSION(S): PRJNA148115

REPOSITORIES: GEO

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Microarray Analysis of Toxicogenomic Effects of Triclosan on Mycobacterium bovis BCG

Project description:Global gene expression analysis of Mycobacterium bovis BCG following Triclosan treatment using Affymetrix GeneChip arrays. Results from this study provide insight into the molecular mechanisms underlying the cellular response of Mycobacterium bovis BCG to Triclosan We conducted three independent microarray experiments (biological replicates) in the absence (control) and the presence (experimental) of triclosan. Fold change was calculated as a ration between the signal averages of three untreated (control) and three triclosan-treated (experimental) cultures for 0, 10 and 60min exposures.

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