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Immune architecture of the colon in ICI-mediated colitis compared with ulcerative colitis

ABSTRACT: Despite clinical success of immune checkpoint inhibitors (ICI), many cancer patients experience immune-related adverse events (irAEs). Among these, ICI-mediated colitis (IC) is prevalent and is associated with a significant burden on patients and healthcare. Despite resemblance to ulcerative colitis (UC) with respect to clinical symptoms and treatment approaches, IC’s specific causes and cellular mechanisms are incompletely understood.

ORGANISM(S): Homo sapiens

PROVIDER: GSE338317 | GEO | 2026/08/01

REPOSITORIES: GEO

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