Genomics

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The Histone Demethylase KDM6B Restrains Hypermetabolic LYVE1+ Perivascular Macrophages and Preserves Adipogenic Balance [ATAC-Seq]


ABSTRACT: We employed ATAC sequencing to study chromatin accessibility in bone marrow-derived macrophages from wild-type and macrophage-specific KDM6B knockout mice following stimulation with LPS and IFNγ. This study was designed to identify genotype-dependent changes in accessible chromatin regions associated with inflammatory macrophage activation.

ORGANISM(S): Mus musculus

PROVIDER: GSE338774 | GEO | 2026/09/01

REPOSITORIES: GEO

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