Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Recognition of ubiquitinated histone H2A constitutes a treatment target for RSF1-driven ovarian cancer

ABSTRACT: This SuperSeries is composed of the SubSeries listed below.

ORGANISM(S): Homo sapiens

PROVIDER: GSE338785 | GEO | 2026/07/16

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Dataset's files

Source:

			Action	DRS
		Other

Items per page:

1 - 1 of 1

Similar Datasets

Recognition of ubiquitinated histone H2A constitutes a treatment target for RSF1-driven ovarian cancer [RNA-seq]

Project description:RNA-seq results revealed that overexpression of RSF1, but not RSF1ΔUAB, induced a gene expression program enriched for cancer stem cell markers. Conversely, overexpression of a UAB domain decoy peptide reduced cell proliferation and blocked the cancer stem cell gene expression programs in OVCAR3 cells. Together, these studies reveal the critical role of recognizing H2Aub in RSF1-driven ovarian cancer and demonstrate that the interaction between RSF1 and H2Aub constitutes a druggable target for treating ovarian cancers with high levels of RSF1.

2025-03-01 | GSE281128 | GEO

Recognition of ubiquitinated histone H2A constitutes a treatment target for RSF1-driven ovarian cancer

Project description:Recognition of ubiquitinated histone H2A constitutes a treatment target for RSF1-driven ovarian cancer

| PRJNA1182350 | ENA

Ubiquitinated histone H2A mapping in Drosophila ML-DmBG3 cells

Project description:Monoubiquitinated histone H2A produced by the Sce/Ring subunit of the Polycomb Repressive Complex 1 (PRC1) was mapped genome-wide in Drosophila ML-DmBG3 cells using chromatin immunoprecipitation followed by hybridization to Affymetrix tiling arrays. ML-DmBG3 chromatin immunoprecipitated with anti-histone H2AK119ub antibody and matching input chromatin were amplified, labeled and hybridized to Affymetrix tiling arrays to determine the locations of ubiquitinated H2A genome-wide.

2013-08-09 | E-GEOD-49634 | biostudies-arrayexpress

Ubiquitinated histone H2A mapping in Drosophila ML-DmBG3 cells

2013-08-09 | GSE49634 | GEO