RNA-seq profiling of U-2 OS osteosarcoma cells expressing scrambled control or Timeless shRNA

ABSTRACT: Timeless and its fission yeast ortholog Swi1 are evolutionarily conserved components of the replication fork protection complex that ensures faithful DNA replication and genome stability. To elucidate the transcriptome-wide impact of Timeless depletion, we treated U-2 OS cells with lentiviruses expressing scrambled control or Timeless-targeting shRNA.

ORGANISM(S): Homo sapiens

PROVIDER: GSE339246 | GEO | 2026/08/19

REPOSITORIES: GEO