Expression data from collecting lymphatic vessels

ABSTRACT: Lymphogenous metastasis is an important event in the progression of many human cancers, and is associated with expression of vascular endothelial growth factor-D (VEGF-D). Changes to the lymphatic vasculature can occur during metastasis, and may aid metastatic spread. We investigated the effect of tumour derived VEGFD on the endothelium of the collecting lymphatic vessels draining primary tumors. We used microarrays to detail the changes in gene expression in the collecting lymphatic endothelium of mice with 293EBNA xenografts compared to 293EBNA xenografts overexpressing VEGFD.

ORGANISM(S): Mus musculus

PROVIDER: GSE34135 | GEO | 2012/01/15

SECONDARY ACCESSION(S): PRJNA150085

REPOSITORIES: GEO