Browse
Submit Data
Databases
API
Help

Dataset Information

0 Views

0 Connections

0 Citations

0 Reanalyses

0 Downloads

Omics score: 0

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.NGR)

ABSTRACT: Detecting differential changes in the peripheral whole-blood transcriptome, post-challenge compared to pre-challenge; using non-globin reduced PAXgene (PAX.NGR) tubes Blood was collected immediately prior to, and two hours after challenge

ORGANISM(S): Homo sapiens

PROVIDER: GSE34159 | GEO | 2012/01/26

SECONDARY ACCESSION(S): PRJNA156469

REPOSITORIES: GEO

ACCESS DATA

Json Xml

Similar Datasets

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.GR)

Project description:Detecting differential changes in the peripheral whole-blood transcriptome, post-challenge compared to pre-challenge; using globin reduced PAXgene (PAX.GR) tubes

2012-01-26 | GSE34158 | GEO

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.NGR)

Project description:Detecting differential changes in the peripheral whole-blood transcriptome, post-challenge compared to pre-challenge; using non-globin reduced PAXgene (PAX.NGR) tubes Blood was collected immediately prior to, and two hours after challenge Preprocessing and filtering were applied to the PAX.NGR dataset using the Factor Analysis for Robust MicroArray Summarization (farms) package in R The Linear Models for MicroArrays (limma) package in R was used to determine differential gene expression using a Benjamini Hochberg FDR of 5%.

2012-01-26 | E-GEOD-34159 | biostudies-arrayexpress

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.GR)

Project description:Detecting differential changes in the peripheral whole-blood transcriptome, post-challenge compared to pre-challenge; using globin reduced PAXgene (PAX.GR) tubes Blood was collected immediately prior to, and two hours after challenge Blood samples from 4 subjects were used to study the effects of globin reduction on differential gene expression Preprocessing and filtering were applied to the PAX.GR dataset using the Factor Analysis for Robust MicroArray Summarization (farms) package in R The Linear Models for MicroArrays (limma) package in R was used to determine differential gene expression using a Benjamini Hochberg FDR of 5%.

2012-01-26 | E-GEOD-34158 | biostudies-arrayexpress

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.NGR and EDTA)

Project description:To determine differential gene expression in peripheral blood of asthmatic individuals undergoing allergen inhalation challenge, post-challenge compared to pre-challenge Blood was collected immediately prior to, and two hours after challenge The 8 PAXgene non-globin reduced (PAX.NGR) samples were combined with 10 EDTA samples (n=9) for one analysis (PAX.NGR+EDTA) comparing gene expression in whole blood between pre and post challenge using the following covariates: tube type, sex, age, PC20 at pre-challenge, and FEV1 after onset and 2h post challenge and the RNA integrity number. Preprocessing and filtering were applied to the PAX.NGR+EDTA dataset using the Factor Analysis for Robust MicroArray Summarization (farms) package in R The Linear Models for MicroArrays (limma) package was used to determine differential gene expression using a Benjamini Hochberg FDR of 5%.

2012-01-26 | E-GEOD-34160 | biostudies-arrayexpress

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge

Project description:This SuperSeries is composed of the following subset Series: GSE34158: Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.GR) GSE34159: Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.NGR) GSE34160: Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.NGR and EDTA) Refer to individual Series

2012-01-26 | E-GEOD-34172 | biostudies-arrayexpress

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (PAX.NGR and EDTA)

Project description:To determine differential gene expression in peripheral blood of asthmatic individuals undergoing allergen inhalation challenge, post-challenge compared to pre-challenge

2012-01-26 | GSE34160 | GEO

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (ER and DR)

2013-09-20 | GSE40240 | GEO

Expression data from peripheral blood - blood draws at Pre and Post time points of Allergen inhalation challenge (ER and DR)

Project description:To determine differential gene expression in peripheral blood of asthmatic individuals undergoing allergen inhalation challenge between early responders (ERs) and dual responders (DRs) following allergen inhalation challenge Blood was collected immediately prior to, and two hours after challenge The change in gene expression (post expression minus pre expression) in ERs was compared with the change in gene expression in DRs using age and sex as covariates Preprocessing and probeset filtering were applied to the entire dataset (28 CEL files) using the Factor Analysis for Robust MicroArray Summarization (farms) package in R The Linear Models for MicroArrays (limma) package was used to determine differential gene expression using a Benjamini Hochberg FDR of 10%.

2013-09-20 | E-GEOD-40240 | biostudies-arrayexpress

Expression data from peripheral blood - blood draws at Pre and Post time points of Methacholine (MCh) inhalation challenge

2011-09-18 | GSE32198 | GEO

Expression data from peripheral blood - blood draws at Pre and Post time points of Methacholine (MCh) inhalation challenge

Project description:Evaluate the effect of methacholine-induced bronchoconstriction on the peripheral whole-blood transcriptome, post-challenge compared to pre-challenge. Blood was collected immediately prior to, and two hours after challenge. 28 total blood samples (14 Pre- and 14 Post-challenge) were analyzed. Robust regression in the Linear Models for MicroArrays (LIMMA) was used to compaire gene expression between Pre and Post time points. No pre-filtering of probe sets was performed prior to statistical analyses. In addtion, and FDR of 10% was used to deteremine signifance of genes.

2011-09-17 | E-GEOD-32198 | biostudies-arrayexpress

OmicsDI is part of the ELIXIR infrastructure

OmicsDI is an Elixir interoperability service. Learn more ›

OmicsDI Databases

PRIDE
PeptideAtlas
MassIVE
JPOST Repository
Physiome Model Repository

EGA
EVA
ENA
LINCS
PAXDB
Cell Collective

MetaboLights
Metabolomics Workbench
MetabolomeExpress
GNPS
BioModels
FAIRDOMHub

ArrayExpress
dbGaP
ExpressionAtlas
GEO
NODE

Information

Databases
Help
API
Contact us
Code on GitHub
Terms of use
Submit Data