Dual inactivation of Akt and ERK by small molecule TIC10 signals Foxo3a nuclear translocation, TRAIL gene induction and potent anti-tumor effects

ABSTRACT: TIC10-induced transcriptional changes at 48hrs in HCT116 p53-null cells (10uM).

ORGANISM(S): Homo sapiens

PROVIDER: GSE34194 | GEO | 2013/03/08

SECONDARY ACCESSION(S): PRJNA149831

REPOSITORIES: GEO