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Comparison of NK cell transcriptomes between C57BL6 and NOD mouse strains

ABSTRACT: Natural Killer (NK) cells are essential for surveillance of stressed, infected and malignant cells in the body. The autoimmune diabetes prone nonobese diabetic (NOD) mouse has a deficiency and dysfunction of NK cells compared to other strains but the molecular basis remains unclear. Here we performed bulk mRNA-seq on bead enriched splenic NK cells from early disease prediabetic 8 week-old female NOD mice as compared with age-matched C57BL6 female mice as controls.

ORGANISM(S): Mus musculus

PROVIDER: GSE342137 | GEO | 2026/08/07

REPOSITORIES: GEO

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