Transcriptomic profiling of tissue from mice with CLP-induced sepsis

ABSTRACT: To investigate the molecular mechanisms underlying sepsis-induced lung injury, we established a murine model of polymicrobial sepsis by cecal ligation and puncture (CLP) in C57BL/6J mice. Lung tissues were harvested 24 h post-surgery, and bulk RNA-sequencing was performed to profile the global transcriptomic changes.

ORGANISM(S): Mus musculus

PROVIDER: GSE342888 | GEO | 2026/08/18

REPOSITORIES: GEO