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Single-nucleus RNA sequencing of mouse hearts after pressure overload-induced heart failure

ABSTRACT: Pressure overload_induced heart failure is associated with extensive cellular remodeling in the heart. To investigate the cell type_specific transcriptional responses regulated by miR_210, single_nucleus RNA sequencing (snRNA_seq) was performed on heart tissues collected from wild_type and miR_210 knockout mice subjected to sham surgery or transverse aortic constriction (TAC). This dataset provides transcriptomic profiles of major cardiac cell populations and can be used to characterize cellular heterogeneity and molecular pathways associated with pressure overload_induced cardiac remodeling.

ORGANISM(S): Mus musculus

PROVIDER: GSE343527 | GEO | 2026/09/03

REPOSITORIES: GEO

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