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Adolescent social isolation alters the single-nucleus transcriptomic landscape of the mouse medial prefrontal cortex

ABSTRACT: This study examined cell-type-specific transcriptional alterations in the medial prefrontal cortex of male mice subjected to adolescent social isolation. Single-nucleus RNA sequencing was used to characterize molecular changes across neuronal and non-neuronal populations, with particular emphasis on parvalbumin interneurons and autophagy-related pathways.

ORGANISM(S): Mus musculus

PROVIDER: GSE344346 | GEO | 2026/08/26

REPOSITORIES: GEO

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