Expression profiling by RNA-Seq in amniotic fluid cells with copy number variations

ABSTRACT: The molecular mechanisms by which copy number variations (CNVs) regulate gene expression remain incompletely elucidated, and the transcriptional response of cultured amniotic fluid cells to CNVs in prenatal diagnosis has not been systematically investigated. This study aims to explore, using RNA-Seq, the effects of CNVs with different clinical significance on the expression of genes within the affected genomic regions.

ORGANISM(S): Homo sapiens

PROVIDER: GSE344419 | GEO | 2026/09/29

REPOSITORIES: GEO