Cigarette smoking alters mRNA expression in human alveolar macrophages

ABSTRACT: Alveolar macrophages from never smokers and active smokers were isolated by bronchoalveolar lavage and gene expression was measured. Chronic cigarette smoke exposure, as occurs in smoker's lungs, leads to significant changes in gene expression. Of note, RNA was isolated immediately following bronchoscopy. Alveolar macrophage levels were >95%.

ORGANISM(S): Homo sapiens

PROVIDER: GSE34517 | GEO | 2012/10/02

SECONDARY ACCESSION(S): PRJNA151409

REPOSITORIES: GEO